This account is pending registration confirmation. Please click on the link within the confirmation email previously sent you to complete registration.
Need a new registration confirmation email? Click here
TheStreet Open House

DIFICID™ (fidaxomicin), A First-in-class Antibiotic, Now Approved In Canada To Treat C. Difficile, A Serious And Life-threatening Infection

TORONTO, July 5, 2012 /CNW/ - Optimer Pharmaceuticals Canada, Inc. announced today the approval of DIFICID (fidaxomicin) by Health Canada for the treatment of Clostridium difficile infection (CDI) in patients 18 years of age and older. DIFICID was approved in Canada on a priority basis recognizing the critical need for new options to treat this disease and is the first new treatment for CDI in over 20 years.

Two large double-blind, comparative, randomized clinical studies were conducted with results published in two leading medical journals, The New England Journal of Medicine and The Lancet Infectious Diseases.  Over 400 Canadian patients participated in the trials, representing over one third of patients studied.  DIFICID was superior to oral vancomycin in reducing CDI recurrence by 46% and shown to be superior in sustaining clinical response for 28 days after treatment i,ii.

DIFICID is the first in a new class of antibiotics called macrocycles.  DIFICID targets C. difficile with a high degree of specificity, and has been shown to preserve the normal gut flora, suppress the production of C. difficile toxins A and B, and inhibit the production of C. difficile spores i. "Collectively, these novel effects may contribute to DIFICID's superior efficacy in reducing the risk of CDI recurrence," stated Dr. Wendy Arnott, Executive Director, Scientific Affairs, Optimer Canada.

CDI has a significant burden on the healthcare system iii,iv,v,vi and on the lives of patients and their families suffering from this disease.

"Clostridium difficile infections (CDI) have been an increasing challenge and burden for the Canadian healthcare system during the last decade vii,viii,ix, and affect the elderly population in a disproportionate manner, iv,v,vii,x " said Dr. Karl Weiss, Professor of Medicine at Maisonneuve-Rosemont Hospital and a member of the Faculty of Medicine at Université de Montréal. "Reducing CDI recurrence is a major objective, knowing that 20 to 30% of affected Canadian patients will experience at least one relapse of the disease, escalating to over 60% after multiple recurrences x."

"Today marks a significant advance in the fight against CDI. Awareness of the burden of CDI on the Canadian healthcare system is high with many healthcare providers, patients, and caregivers impacted by this devastating infection, but what is less commonly understood is that CDI is much more than an acute infection.  In a significant proportion of patients it is a chronic disease given this high rate of recurrence," said Paulash Mohsen, President and Country Manager for Optimer Canada. "We are proud to have the opportunity to bring this first-in-class antibiotic to help Canadian patients in need."

1 of 3

Select the service that is right for you!

COMPARE ALL SERVICES
Action Alerts PLUS
Try it NOW

Jim Cramer and Stephanie Link actively manage a real portfolio and reveal their money management tactics while giving advanced notice before every trade.

Product Features:
  • $2.5+ million portfolio
  • Large-cap and dividend focus
  • Intraday trade alerts from Cramer
  • Weekly roundups
TheStreet Quant Ratings
Try it NOW
Only $49.95/yr

Access the tool that DOMINATES the Russell 2000 and the S&P 500.

Product Features:
  • Buy, hold, or sell recommendations for over 4,300 stocks
  • Unlimited research reports on your favorite stocks
  • A custom stock screener
  • Upgrade/downgrade alerts
Stocks Under $10
Try it NOW

David Peltier, uncovers low dollar stocks with extraordinary upside potential that are flying under Wall Street's radar.

Product Features:
  • Model portfolio
  • Stocks trading below $10
  • Intraday trade alerts
  • Weekly roundups
Dividend Stock Advisor
Try it NOW

Jim Cramer's protege, David Peltier, identifies the best of breed dividend stocks that will pay a reliable AND significant income stream.

Product Features:
  • Diversified model portfolio of dividend stocks
  • Alerts when market news affect the portfolio
  • Bi-weekly updates with exact steps to take - BUY, HOLD, SELL
Real Money Pro
Try it NOW

All of Real Money, plus 15 more of Wall Street's sharpest minds delivering actionable trading ideas, a comprehensive look at the market, and fundamental and technical analysis.

Product Features:
  • Real Money + Doug Kass Plus 15 more Wall Street Pros
  • Intraday commentary & news
  • Ultra-actionable trading ideas
Options Profits
Try it NOW

Our options trading pros provide daily market commentary and over 100 monthly option trading ideas and strategies to help you become a well-seasoned trader.

Product Features:
  • 100+ monthly options trading ideas
  • Actionable options commentary & news
  • Real-time trading community
  • Options TV
To begin commenting right away, you can log in below using your Disqus, Facebook, Twitter, OpenID or Yahoo login credentials. Alternatively, you can post a comment as a "guest" just by entering an email address. Your use of the commenting tool is subject to multiple terms of service/use and privacy policies - see here for more details.
Submit an article to us!
DOW 17,279.74 +13.75 0.08%
S&P 500 2,010.40 -0.96 -0.05%
NASDAQ 4,579.7890 -13.6380 -0.30%

Brokerage Partners

Rates from Bankrate.com

  • Mortgage
  • Credit Cards
  • Auto

Free Newsletters from TheStreet

My Subscriptions:

After the Bell

Before the Bell

Booyah! Newsletter

Midday Bell

TheStreet Top 10 Stories

Winners & Losers

Register for Newsletters
Top Rated Stocks Top Rated Funds Top Rated ETFs