- Narrow spectrum activity that is bactericidal against C. difficile in vitro
- Mainly confined to the gastrointestinal tract
- Minimal effect on intestinal flora, with studies having demonstrated that fidaxomicin treatment did not affect Bacteroides concentrations or other major components of the microbiota in the feces of CDI patients
- Shown to inhibit C. difficile sporulation in vitro
- Suppresses the production of both toxin A and toxin B and inhibits toxin gene expression in vitro
Optimer's DIFICID® (fidaxomicin) Tablets Approved By Health Canada For The Treatment Of Clostridium Difficile Infection And Now Available To Canadian Patients
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