Clinical Safety Data For ChromaDexÂ®'s Patented PTeroPureÂ® (pterostilbene) Released At 6th World Congress On Polyphenols Applications In Paris
IRVINE, Calif., June 13, 2012 /PRNewswire/ -- ChromaDex Corporation (OTCBB: CDXC), an innovative natural products company that provides proprietary, science-based solutions and ingredients to the dietary supplement, food & beverage, animal health, cosmetic and pharmaceutical industries announced today its patented pTeroPure (pterostilbene) was shown to be safe for human consumption according to data from the first clinical trial of the substance. The findings, based on a study with pTeroPure, were presented at the 6th World Congress on Polyphenols Applications in Paris, France on June 7, 2012.(1) Pterostilbene is an antioxidant found in blueberries and other berries and believed by many experts to have a number of health benefits. pTeroPure was named the 2010 North American Most Promising Ingredient of the Year by the independent research company, Frost & Sullivan.
"The safety of pterostilbene has previously been demonstrated in numerous cell and animal studies and we are pleased to find it translates to humans as well," said the study's principle investigator Daniel Riche, PharmD, Cardiometabolic Clinic Coordinator at the University of Mississippi School of Pharmacy. "These results further support pTeroPure's self-affirmed GRAS status and should leave no doubt that it is safe for human use in consumer products."
The study, a double-blind, randomized, placebo-controlled trial, included 80 adults who were given 100 to 250 mg per day of pTeroPure or placebo for 6-8 weeks. The results showed a lack of adverse reactions and no major adverse events. Data analyses from the trial on the effects of pTeroPure on blood pressure, triglycerides, cholesterol and oxidative stress are currently underway, and results are expected to be made public following acceptance in a peer-reviewed journal. The study was a collaboration between the University of Mississippi and ChromaDex.Pterostilbene has superior biological activity, better oral bioavailability and metabolizes more slowly in the body than other antioxidant polyphenols (substances from plants that tend to prevent or neutralize the damaging effects of free radicals), resulting in more prolonged antioxidant activity. Along with a number of other effects, pterostilbene has shown great promise for supporting heart health, cognitive function and anti-aging.
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