The bladder cancer drug aqaziquone blew up Thursday after two late-stage clinical trials failed. Spectrum was counting on seeking U.S. approval for apaziquone later this year. That plan now seems dead, as is the $200-300 million in peak annual revenue Spectrum hoped to generate from the drug.
Spectrum is trying to pivot from the apaziquone disaster by acquiring Allos Therapeutics (ALTH) for $108 million, net of Allos' cash on hand. With the Allos deal, Spectrum gains control of the lymphoma drug Folotyn for a decent price. But Folotyn sales of just $50 million in 2011 (the drug's third year on the market) won't fill the hole left by apaziquone.Shares of Spectrum fell 9% to $11.42 Thursday and are now down 24% for the year. The biotech sector as a whole has been on fire in 2012 but Spectrum isn't keeping pace because very quickly and ominously, the company has become a growth stock without the growth. Sales of Spectrums' colon cancer drug Fusilev grew more than four-fold last year to $153 million, assisted by persistent supply shortages in leucovorin, a cheaper generic alternative. But Fusilev sales will be lucky to grow 10-15% in 2012 and may actually fall if leucovorin becomes more readily available later this year. Sales of Spectrum's non-Hodgkin's lymphoma drug Zevalin did fall last year to $28 million from $29 million in 2010, despite a significant investment in marketing to re-launch the drug in the U.S. The removal of a requirement for a pre-treatment scan late last year may help Spectrum boost Zevalin sales, but only time will tell by how much. On a conference call Thursday, Spectrum CEO Raj Shrotriya said Folotyn sales under his watch could double to $100 million. How? Shrotriya offered no details. Why investors should believe that Spectrum can double sales of a drug Allos has been selling exclusively for three years with little success was not explained. Shrotriya emphasized Folotyn's commercial potential in Europe but failed to mention that European regulators rejected the drug earlier this year. Allos was seeking an appeal of the negative decision but the drug's fate is still uncertain. Without taking into account apaziquone's blowup or the addition of Folotyn, Spectrum was expected to boost 2012 sales by about 11% and earnings by 6%, according to analyst consensus estimates. Folotyn may bolster Spectrum's year-over-year revenue growth but 2012 earnings will probably fall due to the added expense of the Allos acquisition. At Thursday's closing price of $11.06, Spectrum trades for 12 times 2012 earnings, a price-to-earnings ration that seems rich for a company without much growth or an exciting late-stage pipeline.
>To contact the writer of this article, click here: Adam Feuerstein. >To follow the writer on Twitter, go to http://twitter.com/adamfeuerstein. >To submit a news tip, send an email to: email@example.com. Follow TheStreet on Twitter and become a fan on Facebook.
Select the service that is right for you!COMPARE ALL SERVICES
Jim Cramer and Stephanie Link actively manage a real portfolio and reveal their money management tactics while giving advanced notice before every trade.
- $2.5+ million portfolio
- Large-cap and dividend focus
- Intraday trade alerts from Cramer
- Weekly roundups
Access the tool that DOMINATES the Russell 2000 and the S&P 500.
- Buy, hold, or sell recommendations for over 4,300 stocks
- Unlimited research reports on your favorite stocks
- A custom stock screener
- Upgrade/downgrade alerts
Jim Cramer's protege, David Peltier, identifies the best of breed dividend stocks that will pay a reliable AND significant income stream.
- Diversified model portfolio of dividend stocks
- Alerts when market news affect the portfolio
- Bi-weekly updates with exact steps to take - BUY, HOLD, SELL
All of Real Money, plus 15 more of Wall Street's sharpest minds delivering actionable trading ideas, a comprehensive look at the market, and fundamental and technical analysis.
- Real Money + Doug Kass Plus 15 more Wall Street Pros
- Intraday commentary & news
- Ultra-actionable trading ideas
Our options trading pros provide daily market commentary and over 100 monthly option trading ideas and strategies to help you become a well-seasoned trader.
- 100+ monthly options trading ideas
- Actionable options commentary & news
- Real-time trading community
- Options TV