Supply of ZOSTAVAX
Merck cleared all backorders of ZOSTAVAX in late December 2011 and resumed normal, two-day shipping for new orders. Consumers and healthcare providers can visit www.zostavax.com to search an online database called the "Directory to Find ZOSTAVAX" to obtain a list of physician offices or pharmacies within their selected area that offer ZOSTAVAX.
Managed care coverage for ZOSTAVAX
Based on historical coverage information, Merck estimates that over 90 percent of people 60 and older in the United States who have private health insurance are in plans that have approved reimbursement of ZOSTAVAX, and Medicare Part D plans covering over 90 percent of Part D enrollees in the United States have included ZOSTAVAX on formulary. Also, information available to Merck suggests that approximately 35 percent of individuals age 50 to 59 who have health insurance are in plans that have approved reimbursement for ZOSTAVAX for this age group. Whether a person has coverage, and the amount of reimbursement, depends on the person's benefit design, including any applicable co-pays, coverage limitations, co-insurance and/or deductibles and the reimbursement rate adopted by each plan. ZOSTAVAX is also a covered medical benefit for people 60 and older under the U.S. Veterans Health Administration and TRICARE, the health plan for the U.S. Department of Defense Military Health System.Select Safety Information A reduced immune response to ZOSTAVAX was observed in individuals who received concurrent administration of PNEUMOVAX ®23 (Pneumococcal Vaccine Polyvalent) and ZOSTAVAX compared with individuals who received these vaccines 4 weeks apart. Consider administration of the two vaccines separated by at least 4 weeks. Serious vaccine-related adverse reactions that have occurred following vaccination with ZOSTAVAX include asthma exacerbation and polymyalgia rheumatica. Other serious adverse events reported following vaccination with ZOSTAVAX include cardiovascular events (congestive heart failure, pulmonary edema). The rate of serious adverse reactions from Days 0 to 42 postvaccination may be increased. Common adverse reactions occurring in ≥1% of vaccinated individuals during clinical trials include injection-site reactions (erythema, pain/tenderness, swelling, hematoma, pruritus, warmth) and headache.
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