Aveo Pharmaceuticals (AVEO)
ASCO presentation: Full presentation of results from the phase III study of tivozanib in kidney cancer.What we already know: Top-line results from the kidney cancer study were announced in early January with tivozanib demonstrating a progression-free survival of 11.9 months compared to 9.1 months for Nexavar. In a subset of treatment-naive patients, tivozanib PFS was 12.7 months. Key questions: Nexavar performed better than expected in the study, which narrowed the benefit shown by tivozanib and caused some investors to question the tivozanib's true efficacy. Aveo asserts tivozanib's safety data (to be fully disclosed at ASCO) demonstrates superiority over Nexavar.