Cobicistat is Gilead’s proprietary potent mechanism-based inhibitor of cytochrome P450 3A (CYP3A), an enzyme that metabolizes drugs in the body. In addition to studying the agent as part of the Quad, Gilead is also examining cobicistat’s potential in boosting commercially available HIV protease inhibitors.The Quad, elvitegravir and cobicistat are investigational products and their safety and efficacy have not yet been established.
Data Show Gilead’s Quad Regimen For HIV Non-Inferior To Protease-Based Regimen At 48 Weeks In Second Pivotal Phase 3 Study
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