BLUE BELL, Pa., March 5, 2012 /PRNewswire/ -- Inovio Pharmaceuticals, Inc. (NYSE AMEX: INO) announced today that its SynCon® therapeutic vaccine for human papillomavirus (HPV) types 6 and 11, which are associated with head & neck cancers and genital warts, among other conditions, induced strong antigen-specific CD8+ T cells in mice. This vaccine is complementary to Inovio's VGX-3100, a therapeutic vaccine targeting cervical dysplasias and cancers caused by HPV types 16 and 18, which is in a phase II clinical study for CIN 2/3. This positive animal data mirrors the similarly robust T-cell responses induced by VGX-3100 in earlier mice studies. These results were reported in a peer-reviewed paper titled, "Induction of robust cellular immunity against HPV6 and HPV11 in mice by DNA vaccine encoding for E6/E7 antigen," which has been published in Human Vaccines & Immunotherapeutics.
Inovio Therapeutic Vaccine For Head & Neck And Other HPV-Related Cancers Induces Robust T-Cell Immune Response In Mice
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