This Day On The Street
Continue to site right-arrow
ADVERTISEMENT
This account is pending registration confirmation. Please click on the link within the confirmation email previously sent you to complete registration.
Need a new registration confirmation email? Click here
TheStreet Open House

QIAGEN Gains Rights To Genomic Biomarkers For Lung, Brain And Other Cancers To Expand Its Pipeline Of Companion Diagnostics

HILDEN, Germany and GERMANTOWN, Maryland, January 10, 2012 /PRNewswire/ --

 

  • Licenses diagnostic rights for ALK (anaplastic lymphoma kinase) gene, a promising target for novel class of lung cancer drugs, from Insight Genetics, Inc.
  • Acquires rights for diagnosis of IDH1/IDH2 mutations in brain gliomas, acute myelogenous leukemia and other cancers from Personal Genome Diagnostics Inc.
  • Diagnostic tests for these biomarkers are expected to be developed and commercialized for use as prognostic tools or as companion diagnostics for new anticancer drugs

QIAGEN (NASDAQ: QGEN; Frankfurt, Prime Standard: QIA) today announced two agreements with U.S. biotech companies to acquire worldwide exclusive rights to biomarkers that are expected to play an important role in personalized treatment of various cancers.

QIAGEN has entered into a strategic co-development partnership and licensing agreement with Insight Genetics, Inc. of Nashville, Tennessee, for a genetic test covering the ALK (anaplastic lymphoma kinase) biomarker, a promising target for a novel class of lung cancer drugs.

Through a separate agreement between its 89% subsidiary Ipsogen and Personal Genome Diagnostics Inc., of Baltimore, Maryland, QIAGEN has also acquired worldwide exclusive rights to testing for mutations of the IDH1 and IDH2 genes - which are believed to play a role in brain cancers, acute myelogenous leukemia (AML) and certain other malignancies.

"These two new agreements add to our significant activities in further expanding our broad portfolio of novel and relevant biomarkers that can drive personalized healthcare. QIAGEN is a global leader in the emerging market for companion diagnostics, which are increasingly guiding the treatment decisions in various cancers and other diseases," said Peer Schatz, Chief Executive Officer of QIAGEN. "The two agreements announced today add to our portfolio the ALK biomarker, which is being targeted by several pharmaceutical companies for new anti-cancer treatments, as well as the IDH1/IDH2 biomarker, which is currently playing a critical role in intense R&D activity for candidate medicines targeting brain gliomas and other cancers. In addition to providing these assays to researchers, we intend to develop companion diagnostics to make these biomarkers available in combination with new medicines."

The strategic co-development partnership and licensing agreement with Insight Genetics, a molecular diagnostics company focused on enhancing personalized cancer care, gives QIAGEN worldwide exclusive rights to Insight Genetics' diagnostic IP to the ALK gene. The companies will collaborate in the development of a corresponding test that can be clinically validated and marketed by QIAGEN as a companion diagnostic. Mutations of ALK are implicated in non-small cell lung cancer (NSCLC) and other cancers, and several anticancer compounds known as ALK inhibitors, are in clinical trials. One ALK inhibitor has been approved by the FDA, but it is currently paired with a diagnostic method that can be technically challenging and costly.

1 of 2

Check Out Our Best Services for Investors

Action Alerts PLUS

Portfolio Manager Jim Cramer and Director of Research Jack Mohr reveal their investment tactics while giving advanced notice before every trade.

Product Features:
  • $2.5+ million portfolio
  • Large-cap and dividend focus
  • Intraday trade alerts from Cramer
Quant Ratings

Access the tool that DOMINATES the Russell 2000 and the S&P 500.

Product Features:
  • Buy, hold, or sell recommendations for over 4,300 stocks
  • Unlimited research reports on your favorite stocks
  • A custom stock screener
Stocks Under $10

David Peltier uncovers low dollar stocks with serious upside potential that are flying under Wall Street's radar.

Product Features:
  • Model portfolio
  • Stocks trading below $10
  • Intraday trade alerts
14-Days Free
Try it NOW
Only $9.95
Try it NOW
14-Days Free
Try it NOW

Check Out Our Best Services for Investors

Dividend Stock Advisor

David Peltier identifies the best of breed dividend stocks that will pay a reliable AND significant income stream.

Product Features:
  • Diversified model portfolio of dividend stocks
  • Updates with exact steps to take - BUY, HOLD, SELL
Trifecta Stocks

Every recommendation goes through 3 layers of intense scrutiny—quantitative, fundamental and technical analysis—to maximize profit potential and minimize risk.

Product Features:
  • Model Portfolio
  • Intra Day Trade alerts
  • Access to Quant Ratings
Options Profits

Our options trading pros provide over 100 monthly option trading ideas and strategies to help you become a well-seasoned trader.

Product Features:
  • Actionable options commentary and news
  • Real-time trading community
Try it NOW
Try it NOW
Try it NOW
To begin commenting right away, you can log in below using your Disqus, Facebook, Twitter, OpenID or Yahoo login credentials. Alternatively, you can post a comment as a "guest" just by entering an email address. Your use of the commenting tool is subject to multiple terms of service/use and privacy policies - see here for more details.
Submit an article to us!
SYM TRADE IT LAST %CHG

Markets

DOW 17,712.66 +34.43 0.19%
S&P 500 2,061.02 +4.87 0.24%
NASDAQ 4,891.2190 +27.8570 0.57%

Partners Compare Online Brokers

Free Reports

Free Newsletters from TheStreet

My Subscriptions:

After the Bell

Before the Bell

Booyah! Newsletter

Midday Bell

TheStreet Top 10 Stories

Winners & Losers

Register for Newsletters
Top Rated Stocks Top Rated Funds Top Rated ETFs