Hypoglycemic events were more frequent in the dapagliflozin groups (9.7% in 2.5 mg group, 10.3% in 5 mg group, 11.3% in 10 mg group) compared to the placebo group (6.8%), with no patients discontinuing treatment due to hypoglycemia. There was one major episode of hypoglycemia in the dapagliflozin 2.5 mg group.The percentage of patients with events suggestive of genital infections was higher for dapagliflozin added to glimepiride compared to placebo added to glimepiride, as follows: 5.2% with dapagliflozin 2.5 mg, 6.2% with dapagliflozin 5 mg and 8.6% for dapagliflozin 10 mg compared to 1.4% with placebo added to glimepiride. Overall, events suggestive of genital infections were higher in females than in males.
New Data Show Investigational Compound Dapagliflozin When Added To Glimepiride Maintained Reductions In Blood Sugar Levels In Adults With Type 2 Diabetes Over 48 Weeks Of Treatment
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