Eric Schadt, Ph.D., Chief Scientific Officer of Pacific Biosciences and co-author of the paper commented: “We have reached a new era in which communities of researchers can rapidly share large-scale data sets and analyses vital for public health. Sequencing genomes in hours, as opposed to days or weeks, with unprecedented read lengths is the emerging hallmark of third generation DNA sequencing. The long PacBio RS reads enabled a PacBio-only de novo genome assembly, a key component of new pathogen characterization, as well as deeper insights into structural variants.”The paper is available at www.nejm.com. The data are available for the bioinformatics community at the PacBio developer’s network (DevNet) web site ( www.pacbiodevnet.com), where a suite of open source tools and other resources designed for SMRT sequence data are available to analyze the information. A summary of the sequencing project appears on the Pacific Biosciences website at http://blog.pacificbiosciences.com. More information about SMRT technology is available at www.pacificbiosciences.com .
Pacific Biosciences DNA Sequencing Technology Yields New Insights Into Virulence And Evolution Of German E. Coli Pathogen
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