According to the Center for International Blood and Marrow Transplant Research (CIBMTR), there are now over 60,000 autologous and allogeneic bone marrow transplants performed annually worldwide, a number projected to further increase due to the anticipated growth in incidence of hematologic malignancies associated with an aging population.Of the total transplants performed annually worldwide, approximately 25,000 are allogeneic. This number represents less than 30 per cent of individuals who would otherwise be eligible to receive an unrelated donor bone marrow transplant because for the rest a fully matched donor cannot be found. Perfect matching is required for adult marrow transplants because of the very high risk of potentially life-threatening GVHD when unmatched transplants are performed. GVHD still occurs in as many as 60 per cent of patients who receive fully matched bone marrow transplants from unrelated adult donors.
Mesoblast Receives FDA Clearance For Phase 3 Bone Marrow Transplant Trial
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