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Radient Pharma Readies Onko-Sure Data

TUSTIN, Calif. (TheStreet) -- Here are some updates, observations and answers to common questions about Radient Pharmaceuticals (RPC) as the clock ticks down to the release of data from a clinical validation study of the company's cancer monitoring test Onko-Sure:

Is Onko-Sure more accurate than the carcinoembryonic antigen (CEA) test in monitoring colon cancer?

That's what Radient believes, especially in patients with early-stage colon cancer, which is why the company (and its retail investor fan base) is placing so much emphasis on data from this ongoing validation study. Results are expected before the end of the quarter, which is Thursday.

Both Onko-Sure and CEA are already cleared by the Food and Drug Administration as blood-based tests to monitor the progression of colon cancer. In order to show superiority of Onko-Sure over CEA, Radient purchased from the Mayo Clinic 976 blood samples taken from colon cancer patients in various stages of the disease.

The Mayo Clinic tested these samples using the CEA test, while Radient is testing the same samples using Onko-Sure. The results from the two tests will then be compared against each other. Radient is especially hopeful that Onko-Sure will prove to be more accurate than the CEA test in patients with early-stage colon cancer.

Wait! You just said the Mayo Clinic tested these samples using the CEA test, which means Mayo really is partnered with Radient on this Onko-Sure test! You're a liar!

Wow, take off the tin-foil hat. Radient bought colon cancer blood samples from Mayo tested with CEA. That's it. Radient is conducting the actual validation study on its own. Recall Mayo's public statement regarding the Onko-Sure study:

"Mayo is not engaged in clinical studies with Radient and does not have a partnership agreement with Radient."

Think of this controvery another way: If Mayo were working with Radient on this Onko-Sure study (as Radient has claimed), then why isn't Mayo testing the colon cancer blood samples with CEA and Onko-Sure? Wouldn't it make more sense for Mayo, one of the most prestigious and independent research hospitals in the country, to conduct all the testing? It would certainly lend additional credibility to the results, whatever they might be.

But Mayo isn't doing all the testing. Instead, Radient ran the Onko-Sure tests on its own, which is not exactly the most unbiased way of conducting a clinical trial, even if a third-party statistical group is expected to tabulate the results.

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