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ATMI Announces Helium Integrity Testing For Single-Use Bioprocess Vessels

DANBURY, Conn. and NEW YORK, March 29, 2011 (GLOBE NEWSWIRE) -- Interphex  -- ATMI, Inc. (Nasdaq:ATMI) today announced it has introduced Helium Integrity Testing on its single-use Integrity™ Bioprocess Vessels (BPVs). The deployment of Helium Integrity Testing (HIT) to confirm product integrity is unique in the industry and its application to fully-assembled bags takes quality assurance to a new level. ATMI's HIT, for which patents have been applied, is likely the most sensitive and reproducible technology for leak-detection in the industry.

The HIT process involves flooding a fully-assembled vessel with a prescribed amount of helium and noting any helium escape that can be detected. Specialized helium sensors that are exterior to the vessel can detect holes as small as 10 microns. While tests of this type have been attempted before, no company has ever fully qualified and comprehensively deployed it. After extensive development of the technology for adaptation to wide-spread, practical application, HIT is being piloted on ATMI's 2-D Integrity bags at its North American life sciences manufacturing facility in Bloomington, MN. The company plans to deploy HIT across its full Integrity line of single-use technologies in a phased approach.

"The integrity of sterile vessels used in biopharmaceutical processes is of critical importance," commented Jeffery Craig, Global Director, Business Development & Marketing, ATMI LifeSciences. "Leaks in the bags obviously compromise the quality of the product so, by starting to deploy HIT, we are providing customers with additional peace of mind beyond our already stringent integrity testing, and continuing to ensure that ATMI employs the most cutting-edge integrity testing standards in the market. To address market needs for quality, ultra-cleanliness, and vessel integrity, we always manufacture in Class V space with vertical laminar air flow to minimize particle count, and we execute 100% integrity testing of fully assembled bags. The addition of HIT to our integrity testing procedures allows us to provide unprecedented quality assurance."

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