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American CareSource And MedFocus Imaging Network Sign National Agreement

American CareSource Holdings, Inc. (NASDAQ: ANCI), the nation’s leading ancillary health care system, announced today the signing of MedFocus Radiology Network (“MedFocus”), based in Santa Monica, a nationwide radiology provider network with over 3,000 quality radiology sites in 45 states as well as the District of Columbia and Puerto Rico.

“Diagnostic imaging is an important cost concern to our clients. Our commitment is to provide the best services at the lowest possible cost for our clients. This was an important consideration when pursuing a relationship with MedFocus,” said David S. Boone, President and Chief Executive Officer of American CareSource. “The MedFocus network of radiology and diagnostic imaging locations works with the latest equipment and technology to provide our clients with convenient, nationwide access to radiology and diagnostic imaging services at the most cost effective pricing. MedFocus is a valuable network partner and through this relationship, American CareSource’s network will expand up to 3,000 new imaging sites.”

“We are excited to partner with American CareSource to bring this opportunity to our network providers,” states Stephen B. Meisel, MD, President and Medical Director of MedFocus. “Our relationship with American CareSource validates our mission to continually enhance options for our provider locations with various health plans. We continue to make strides in forging these associations because of their value to our network providers.”

About American CareSource Holdings, Inc.

American CareSource Holdings is the first national, publicly traded ancillary care network services company. The Company offers a comprehensive national network of over 5,000 ancillary service providers at more than 36,000 sites through its subsidiary, Ancillary Care Services. Ancillary Care Services provides ancillary health care services through its network that offers cost effective alternatives to physician and hospital-based services. This market is estimated at $574 billion and has grown to 30% of total national health expenditures. These providers offer services in 31 categories including laboratories, dialysis centers, free-standing diagnostic imaging centers, non-hospital surgery centers, as well as durable medical equipment such as orthotics and prosthetics and others. The Company's ancillary network and management provides a complete outsourced solution for a wide variety of health care payors and plan sponsors including self-insured employers, indemnity insurers, PPOs, HMOs, third party administrators and both federal and local governments. For additional information, please visit www.anci-care.com.

ANCI-F

Safe Harbor Statement Under the Private Securities Litigation Reform Act of 1995:

Any statements that are not historical facts contained in this release, including with respect to the Company’s plans, objectives and expectations for future operations, projections of the Company’s future operating results or financial condition, and expectations regarding the health care industry and economic conditions, are forward-looking statements. Substantial risks and uncertainties could cause actual results to differ materially from those indicated by forward-looking statements, including, but not limited to, changes in national health care policy, regulation, general economic conditions, demand for ancillary services, pricing, competition, market acceptance/preference, the Company’s ability to integrate with its clients, changes in the business decisions by key clients or consolidation in the industry affecting them, the Company’s inability to attract or maintain providers or clients or to manage growth, implementation and performance difficulties, and other risk factors detailed from time to time in the Company’s periodic filings with the Securities and Exchange Commission. Except as otherwise required by law, the Company undertakes no obligation to update or revise these forward-looking statements.

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