Integra LifeSciences Introduces Advanced Orthobiologics For Extremity Reconstruction

PLAINSBORO, N.J., Feb. 16, 2011 (GLOBE NEWSWIRE) -- Integra LifeSciences Holdings Corporation (Nasdaq:IART) announced today the launch of Trel-XPress™ Demineralized Bone Matrix, expanding its portfolio of bone grafting substitutes for the orthopedic extremity reconstruction surgeon, which includes Integra OS® Osteoconductive Scaffold, a synthetic bone void filler manufactured from beta tri-calcium phosphate and type I bovine collagen; Trel-X(TM), a demineralized bone matrix; and Trel-XC®, a demineralized bone matrix premixed with cancellous bone.

Trel-XPress™ Demineralized Bone Matrix is powered by Accell® technology and is composed of an optimized blend of particulate Demineralized Bone Matrix (DBM), Integra's proprietary Accell® Bone Matrix (ABM), and a reverse phase medium poloxamer. ABM is an open structured and more dispersed form of DBM, providing a high surface area environment that encourages bone formation.

"Integra offers one of the most comprehensive orthobiologics portfolios for the extremity reconstructive surgeon, and the introduction of Trel-XPress™ Demineralized Bone Matrix reinforces our commitment to give surgeons more solutions for their patients," said Robert Paltridge, President of Integra Extremity Reconstruction. 

Surgeons frequently remove bone from the spine, extremities and pelvis that has been damaged by trauma, degenerative conditions and aging.  Bone grafts are generally needed to fill in these defects and aid the body in regenerating new bone.  Bone grafts provide a foundation or scaffold for the patient's body to grow new bone, and encourage new bone production and bone fusion.

Surgeons have historically obtained healthy bone graft material from the patient's own body, often from the iliac crest of the pelvis. Sourcing bone graft material in this manner requires additional surgery that may cause post-operative pain, and there is also a limit on how much of the patient's bone may be removed from the donor site.

Trel-XPress™ Demineralized Bone Matrix offers an alternative for use as a bone graft in orthopedic extremity reconstruction surgeries. It may reduce the need to harvest the patient's own bone, sparing the patient additional surgery and limiting the risk of any associated complications.