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Rockwell Medical To Present Data At American Society Of Nephrology (ASN) Annual Meeting

WIXOM, Mich., Nov. 3, 2010 (GLOBE NEWSWIRE) -- Rockwell Medical (Nasdaq:RMTI), a fully-integrated biopharmaceutical company offering innovative products and services targeting end-stage renal disease (ESRD), chronic kidney disease (CKD), and iron deficiency anemia, announced today that two Soluble Ferric Pyrophosphate (SFP) abstracts have been accepted for presentation at the American Society of Nephrology (ASN) meeting being held on November 16 – 21 in Denver, Colorado.

Data will be presented during the ASN meeting for the Company's late-stage investigational drug SFP, which is being studied for the treatment of iron-deficiency anemia in ESRD patients, at the following poster session:

  • Title: Reduced ESA Requirement by Continuous Delivery of Soluble Ferric Pyrophosphate (SFP) via Dialysate in CKD−HD Patients ; Poster Board #: F−PO1392; Friday, November 19, 2010 ; 10:00am−2:30pm
  • Title: IV Iron Therapy Leads to Iron Overload in CKD-HD Patients ; Poster Board #: F-PO1395; Friday, November 19, 2010 ; 10:00am-2:30pm

Full abstracts can be viewed on the ASN website at  http:// www.asn-online.org

About SFP:

SFP is a novel, investigational, continuous iron therapy in late-stage clinical development, designed to treat iron deficiency anemia in ESRD patients.  In contrast to intravenous (IV) iron delivery, SFP is a proprietary, water-soluble iron that travels to the bloodstream and binds directly to apo-transferrin and then travels to bone marrow to assist in forming a healthy red blood cell, similar to normal physiologic dietary iron intake.  SFP is a continuous iron replacement treatment, delivering small doses of iron during every dialysis session, to replenish the 5-7mg of iron lost during the dialysis procedure, thereby maintaining hemoglobin in the target range as per Kidney Disease Quality Outcomes Initiative (KDQOI) recommendations. Clinical trial data to date suggests that SFP, delivered via dialysate during each dialysis treatment, maintains optimal iron balance and avoids liver toxicity while decreasing associated drug administration costs. Academic studies have shown that more frequent maintenance doses of iron improve therapeutic response to erythropoiesis-stimulating agents (ESA's), thereby decreasing the ESA doses needed to maintain hemoglobin in the target range. Rockwell has licensed exclusive world-wide rights to manufacture and sell SFP and has obtained patent protection for SFP in multiple countries, including the three largest dialysis markets in the world: the United States, Japan, and the European Union. Based on current market data, the U.S. dialysis market for IV iron is approximately $560 million annually while global market potential is approximately $1 billion.

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