Evotec And Shionogi Enter Fragment-Based Drug Discovery Alliance
HAMBURG, Germany, Oct. 5, 2010 (GLOBE NEWSWIRE) -- Evotec AG (Frankfurt:EVT) (TecDAX) today announced that it has entered into a multiple target drug discovery collaboration with Shionogi & Co Ltd. (Tokyo and Osaka Stock Exchanges:4507), to identify small molecule modulators of various protein-protein interaction targets.
Evotec will apply its proprietary and integrated fragment-based drug discovery platform, EVOlution™ to the programme. The key benefit of this platform for the selection of target-specific strategies is its versatility, combining biochemical and biophysical techniques including nuclear magnetic resonance (NMR), surface plasmon resonance (SPR) and X-ray crystallography. Within this collaboration, EVOlution™ will be used to investigate protein-protein interactions on targets selected by Shionogi.
Dr Mario Polywka, COO of Evotec stated: "We are extremely pleased that Shionogi has decided to undertake these projects with Evotec. Our proprietary fragment-based drug discovery platform has shown that it adds significant value to our partner's programmes and we look forward to supporting Shionogi in finding novel treatments for inflammation and infectious diseases."No financial details are disclosed. About EVOlution TM EVOlution TM is Evotec's fragment-based drug discovery platform which combines biochemical and biophysical techniques including nuclear magnetic resonance (NMR), surface plasmon resonance (SPR) and X-ray crystallography for the screening of low molecular weight compounds and fragments. By the combination of the orthogonal screening technologies, Evotec's fragment screening platform is capable of screening a more diverse set of biological targets than other fragment screening approaches, as well as being able to screen the fragments in a high-throughput mode. The benefit of this is the ability to identify active fragments for numerous classes of biological targets in a short space of time. For further information, please see: www.evotec.com/ fragment-based drug discovery About Fragment-based Drug Discovery Fragment-based drug discovery (FBDD) is a drug discovery strategy that utilises very small molecules - fragments of more complex molecules – to generate efficient starting points for drug discovery. This approach thus provides the opportunity to effectively manage the molecular weight and overall complexity of drug candidates, a recognised success factor in drug development.
Select the service that is right for you!COMPARE ALL SERVICES
Jim Cramer and Stephanie Link actively manage a real portfolio and reveal their money management tactics while giving advanced notice before every trade.
- $2.5+ million portfolio
- Large-cap and dividend focus
- Intraday trade alerts from Cramer
- Weekly roundups
Access the tool that DOMINATES the Russell 2000 and the S&P 500.
- Buy, hold, or sell recommendations for over 4,300 stocks
- Unlimited research reports on your favorite stocks
- A custom stock screener
- Upgrade/downgrade alerts
Jim Cramer's protege, David Peltier, identifies the best of breed dividend stocks that will pay a reliable AND significant income stream.
- Diversified model portfolio of dividend stocks
- Alerts when market news affect the portfolio
- Bi-weekly updates with exact steps to take - BUY, HOLD, SELL
All of Real Money, plus 15 more of Wall Street's sharpest minds delivering actionable trading ideas, a comprehensive look at the market, and fundamental and technical analysis.
- Real Money + Doug Kass + 15 more Wall Street Pros
- Intraday commentary & news
- Ultra-actionable trading ideas
Our options trading pros provide daily market commentary and over 100 monthly option trading ideas and strategies to help you become a well-seasoned trader.
- 100+ monthly options trading ideas
- Actionable options commentary & news
- Real-time trading community
- Options TV