Myrexis To Provide Update On The Company's Cancer Metabolism Inhibitor At Upcoming Scientific Meetings
SALT LAKE CITY, Sept. 16, 2010 (GLOBE NEWSWIRE) -- Myrexis, Inc. (Nasdaq:MYRX), a biotechnology company focused on discovering, developing, and commercializing novel treatments for cancer, today announced it will present a poster at the Cancer and Metabolism: Pathways to the Future meeting in Edinburgh, Scotland, as well as two additional posters at the 22 nd European Organisation for Research and Treatment of Cancer (EORTC), National Cancer Institute (NCI) and American Association for Cancer Research (AACR) Symposium on "Molecular Targets and Cancer Therapeutics" November 16-19, 2010, in Berlin, Germany.
The posters will highlight key findings from Myrexis' cancer metabolism inhibitor (CMI) program, including the Company's potential best-in-class Nampt inhibitor, MPC-9528, which is currently in preclinical IND studies and has demonstrated flexible dosing and dramatic tumor regression across multiple tumor types.
|Cancer & Metabolism: Pathways to the Future; Edinburgh, Scotland|
|Title:||MPC-9528, a cancer metabolism inhibitor,|
|demonstrates improved efficacy in a Naprt1 deficient|
|cancer xenograft model with co-administration of|
|efficacy in a Naprt1 deficient nicotinic acid.|
|Date & Time:||September 20, 2010; 9AM - 5PM British Time (BT)|
|22 nd EORTC-NCI-AACR Symposium on "Molecular Targets and Cancer Therapeutics"; Berlin, Germany|
|Title:||Anti-Tumor Activity of MPC-9528, GMX1778, and|
|APO866: Nampt Inhibitors of Three Structural Classes|
|Date & Time:||Nov 17, 2010; 12 PM – 2 PM Central European Time|
|Title:||The Nampt inhibitor MPC-9528 and the PARP|
|inhibitor olaparib synergize in killing a BRCA--|
|deficient cancer cell line|
|Date & Time:||Nov 17, 2010; 12 PM – 2 PM CET|
About MPC-9528MPC-9528 is an orally-bioavailable, small molecule Cancer Metabolism Inhibitor (CMI) discovered by Myrexis that is currently in preclinical development for the treatment of a variety of cancers. MPC-9528 potently and selectively inhibits nicotinamide phosphoribosyltransferase, or Nampt, an enzyme critical for converting nicotinamide into nicotinamide adenine dinucleotide (NAD). Cellular processes such as glucose metabolism, DNA repair and gene expression require and consume NAD. Cancer cells have increased NAD requirements and are highly sensitive to NAD depletion. Blocking the Nampt-NAD pathway severely inhibits cancer cell metabolism, resulting in energy deprivation and ultimately cell death. In non-clinical models, MPC-9528 causes dramatic tumor regressions across multiple tumor types.
Select the service that is right for you!COMPARE ALL SERVICES
Jim Cramer and Stephanie Link actively manage a real portfolio and reveal their money management tactics while giving advanced notice before every trade.
- $2.5+ million portfolio
- Large-cap and dividend focus
- Intraday trade alerts from Cramer
- Weekly roundups
Access the tool that DOMINATES the Russell 2000 and the S&P 500.
- Buy, hold, or sell recommendations for over 4,300 stocks
- Unlimited research reports on your favorite stocks
- A custom stock screener
- Upgrade/downgrade alerts
Jim Cramer's protege, David Peltier, identifies the best of breed dividend stocks that will pay a reliable AND significant income stream.
- Diversified model portfolio of dividend stocks
- Alerts when market news affect the portfolio
- Bi-weekly updates with exact steps to take - BUY, HOLD, SELL
All of Real Money, plus 15 more of Wall Street's sharpest minds delivering actionable trading ideas, a comprehensive look at the market, and fundamental and technical analysis.
- Real Money + Doug Kass + 15 more Wall Street Pros
- Intraday commentary & news
- Ultra-actionable trading ideas
Our options trading pros provide daily market commentary and over 100 monthly option trading ideas and strategies to help you become a well-seasoned trader.
- 100+ monthly options trading ideas
- Actionable options commentary & news
- Real-time trading community
- Options TV