This Day On The Street
Continue to site right-arrow
This account is pending registration confirmation. Please click on the link within the confirmation email previously sent you to complete registration.
Need a new registration confirmation email? Click here
TheStreet Open House

The ASCO Weekend Live Blog Recap

The message is essentially this: Treat multiple myeloma patients with Revlimid continuously. The Celgene data on Revlimid maintenance in multiple myeloma were very strong. There was a significant benefit for Revlimid in progression-free survival, overall survival data not yet mature enough.

Street expectations are high for Revlimid but if the strength of these multiple myeloma maintenance data continue, Revlimid sales estimates are going higher.

Celgene showed some very compelling, early data using Revlimid plus Rituxan in patients with follicular lymphoma. One of these days, the Revlimid/Rituxan regimen could become the next standard of care for lymphoma patients, replacing Rituxan-CHOP.

On Oxigene (OXGN):

This is a phase II study of Oxigene's experimental drug CA4P + Avastin + chemo (the CA4P arm) compared to Avastin + chemo (standard care arm) in patients with treatment naive non-small cell lung cancer.

Interim efficacy data was available on 30 patients, 15 in each arm.

Median progression-free survival (PFS) was 6.9 months in the CA4P arm compared to 6.2 months in the standard care arm. The hazard ratio was reported as 0.70, which means 30% reduction in the odds of tumor progression. This result was not statistically significant.

My take: Interesting data but not statisically significant, with small patient numbers. The PFS difference, numerically, is really quite small. What happens when larger numbers of patients are enrolled?

Tumor response was 60 percent in the CA4P arm compared to 40 percent in the standard therapy arm. All were partial responses. There was a lot more stable disease in the standard therapy arm compared to the CA4P arm, more than double. It would have been better for CA4P if that stable disease outcome were reversed.

Median overall survival was not reached but there is a trend in favor of CA4P. Again, this trend is not statistically significant. I wouldn't expect it to be because of the small patient numbers.

Overall impression: Meh. We definitely need to see more here. These data are early.

On YM BioSciences (YMI):

I checked out the YM BioSciences poster on nimotuzumab late yesterday. I have to say, the data -- four-year survival follow up from a phase IIb study of head-neck cancer patients -- looks pretty good.

3 of 4

Check Out Our Best Services for Investors

Action Alerts PLUS

Jim Cramer and Stephanie Link reveal their investment tactics while giving advanced notice before every trade.

Product Features:
  • $2.5+ million portfolio
  • Large-cap and dividend focus
  • Intraday trade alerts from Cramer
Quant Ratings

Access the tool that DOMINATES the Russell 2000 and the S&P 500.

Product Features:
  • Buy, hold, or sell recommendations for over 4,300 stocks
  • Unlimited research reports on your favorite stocks
  • A custom stock screener
Stocks Under $10

Jim Cramer's protégé, David Peltier, uncovers low dollar stocks with extraordinary upside potential that are flying under Wall Street's radar.

Product Features:
  • Model portfolio
  • Stocks trading below $10
  • Intraday trade alerts
Try it NOW
Try it NOW
Try it NOW

Check Out Our Best Services for Investors

Dividend Stock Advisor

Jim Cramer's protégé, David Peltier, identifies the best of breed dividend stocks that will pay a reliable AND significant income stream.

Product Features:
  • Diversified model portfolio of dividend stocks
  • Updates with exact steps to take - BUY, HOLD, SELL
Trifecta Stocks

Every recommendation goes through 3 layers of intense scrutiny—quantitative, fundamental and technical analysis—to maximize profit potential and minimize risk.

Product Features:
  • Model Portfolio
  • Intra Day Trade alerts
  • Access to Quant Ratings
Options Profits

Our options trading pros provide over 100 monthly option trading ideas and strategies to help you become a well-seasoned trader.

Product Features:
  • Actionable options commentary and news
  • Real-time trading community
Try it NOW
Try it NOW
Try it NOW
To begin commenting right away, you can log in below using your Disqus, Facebook, Twitter, OpenID or Yahoo login credentials. Alternatively, you can post a comment as a "guest" just by entering an email address. Your use of the commenting tool is subject to multiple terms of service/use and privacy policies - see here for more details.
Submit an article to us!


DOW 17,387.21 -291.49 -1.65%
S&P 500 2,029.55 -27.54 -1.34%
NASDAQ 4,681.4970 -90.2660 -1.89%

Partners Compare Online Brokers

Free Reports

Free Newsletters from TheStreet

My Subscriptions:

After the Bell

Before the Bell

Booyah! Newsletter

Midday Bell

TheStreet Top 10 Stories

Winners & Losers

Register for Newsletters
Top Rated Stocks Top Rated Funds Top Rated ETFs