Abstract No. 8012Indication: non-Hodgkin's lymphoma Clinical Trial: Btk inhibitor PCI-32765 monotherapy induces objective responses in patients with relapsed aggressive NHL: Evidence of antitumor activity from a phase I study. Presentation Time: Saturday, June 5. Oral session. Notes: Interim data from 19 of 22 patients are reported in Thursday night's ASCO abstract, with a 42% overall response rate. This includes 1 patient reporting a complete response and 7 patients with partial responses. All patients in the study were diagnosed with advanced NHL, previously treated with a median of three therapies. Phase II studies of PCI-32765 are planned. Since December, Pharmacyclics shares have gone from $2 to $7 as the company puts a history of drug development failures behind it and builds a new research pipeline.
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