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Biotech Calendar: Key Clinical Trial Dates

Company: Oxigene (OXGN)
Drug/indication: Zybrestat for non-small cell lung cancer
Clinical trial event: Phase II results
Timing: 2009

The phase II study adds Zybrestat to a standard first-line regimen for lung cancer for Avastin and chemotherapy. The study enrolled 60 patients and is using progression-free survival as the primary endpoint.

Company: Protalix Biotherapeutics (PLX)
Drug/indication: prGCD for Gaucher's disease
Clinical trial event: Phase III results
Timing: Fourth quarter

Protalix says it will seek FDA approval for prGCD if results are positive from this pivotal phase III study. The drug, if approved, would compete against Genzyme's Cerezyme.

Company: Repros Therapeutics (RPRX)
Drug/indication: Proellex for uterine fibroids
Clinical trial event: Phase III results
Timing: Fourth quarter

This is the first of two phase III studies required for Repros to seek regulatory approval of Proellex. Results from the second study are expected early next year.

Company: Vertex Pharmaceuticals (VRTX - Get Report)
Drug/indication: Telaprevir for hepatitis C
Clinical trial event: Phase II twice-daily dosing data
Timing: 2009

Vertex will release final data from a phase II study investigating whether telaprevir can be dosed twice daily instead of three times daily.

Adam Feuerstein writes regularly for In keeping with TSC's editorial policy, he doesn't own or short individual stocks, although he owns stock in He also doesn't invest in hedge funds or other private investment partnerships. Feuerstein appreciates your feedback; click here to send him an email.
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