Market Features
Genzyme Shuts Down Facility After Detecting Virus
NEW YORK (AP) — Genzyme Corp. said Tuesday it shut down a key production facility as it cleans viral contamination that has been slowing down the process for making supplies of two biotech-based drugs.
The biotechnology company said the virus, which is not harmful to people, was detected in one of six bioreactors at a facility in Boston, and as a precaution, it will shut down until the end of July to properly clean all of its equipment. Bioreactors are used in the production of living cells, which are in turn used to make the biotech-based drugs Cerezyme and Fabrazyme. Supplies of those drugs will be constrained because of the shutdown. Fabrazyme treats an inherited disorder known as Fabry disease, which is caused by the buildup of a particular type of fat in the body's cells. Cerezyme treats Gaucher disease, an enzyme disorder that can result in liver and neurological problems. Genzyme said it has confirmed that the virus was the cause of two previous declines in cell productivity at the facility — located in the Boston neighborhood of Allston — and another one in Geel, Belgium. The company is adding steps to increase raw materials screening and viral removal processes. Meanwhile, Cerezyme and Fabrazyme inventories are not sufficient to meet global demand.TheStreet Premium Services
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