Thursday's Health Winners & Losers
Clinical trial news burned a few biotech stocks Thursday, while brighter trial updates kept others on higher ground.
NPS Pharmaceuticals (NPSP) gave up $1.50, or 27%, to $4.17 after its drug for short bowel syndrome failed to meet its goal in a phase III study. Specifically, the goal was a reduction in parenteral nutrition (being fed intravenously) of at least 20%.
The lower-dose group did show a statistically significant reduction compared with placebo, but according to the study design, the high-dose group needed to show statistical significance before the results for the low-dose group could be considered. The company said it will meet with the Food and Drug Administration to discuss the results.
Also, CuraGen (CRGN) said its velafermin for the prevention of mouth ulcerations in patients undergoing chemotherapy treatment failed a phase II clinical trial, and it is discontinuing its development. The company is now focusing on belinostat in phase II clinical trials for solid tumors and malignancies. Shares fell 48 cents, or 33%, to 98 cents.NPS and CuraGen both tugged at the Nasdaq biotechnology index, which was down $2.15, or 0.2%. Small-cap Cortex Pharmaceuticals (COR) crashed after reporting that the FDA sent a final rejection to the company's investigational new-drug application (IND) to study its CX717 in a Phase IIb study in attention deficit hyperactivity disorder, based on results of animal toxicology studies that Cortex filed.
Select the service that is right for you!COMPARE ALL SERVICES
Jim Cramer and Stephanie Link actively manage a real portfolio and reveal their money management tactics while giving advanced notice before every trade.
- $2.5+ million portfolio
- Large-cap and dividend focus
- Intraday trade alerts from Cramer
- Weekly roundups
Access the tool that DOMINATES the Russell 2000 and the S&P 500.
- Buy, hold, or sell recommendations for over 4,300 stocks
- Unlimited research reports on your favorite stocks
- A custom stock screener
- Upgrade/downgrade alerts
Jim Cramer's protege, David Peltier, identifies the best of breed dividend stocks that will pay a reliable AND significant income stream.
- Diversified model portfolio of dividend stocks
- Alerts when market news affect the portfolio
- Bi-weekly updates with exact steps to take - BUY, HOLD, SELL
All of Real Money, plus 15 more of Wall Street's sharpest minds delivering actionable trading ideas, a comprehensive look at the market, and fundamental and technical analysis.
- Real Money + Doug Kass Plus 15 more Wall Street Pros
- Intraday commentary & news
- Ultra-actionable trading ideas
Our options trading pros provide daily market commentary and over 100 monthly option trading ideas and strategies to help you become a well-seasoned trader.
- 100+ monthly options trading ideas
- Actionable options commentary & news
- Real-time trading community
- Options TV