Friday's Small-Cap Winners & Losers

Cytomedix (GTF Quote) was one of the biggest winners, both among small-cap stocks and overall, amid a mostly bullish session Friday.

Shares of the Rockville, Md., biotech company skyrocketed some 125% after the Food and Drug Administration approved its wound-closing AutoloGel System for use on various sorts of ulcers, as well as for the management of mechanically or surgically debrided wounds. Shares soared $1.47 to $2.64.

HandHeld Entertainment (ZVUE Quote) also rode high after the maker of Zvue portable media players announced that comScore Media Matrix has named it the "fastest growing Web property" for August, citing a 327% surge in unique U.S. visitors to its Web-based network vs. July. Shares of the San Francisco-based company vaulted more than 65% to $2.90.

Elsewhere, Cowen & Co. started coverage on Savient Pharmaceuticals (SVNT Quote) with an outperform rating, saying its proposed gout treatment Puricase -- meant for patients who haven't responded to other treatments -- is promising and has significant revenue potential. Shares leapt 81 cents, or 6.1%, to $14.06.

The Russell 2000 and the S&P SmallCap 600 added 0.4% and 0.1%, respectively, boosted by gains at both Savient and at Genesco (GCO Quote), which filed a lawsuit seeking to force Finish Line (FINL Quote) to close the $1.5 billion merger the footwear retailers inked in June.

Earlier this month, UBS -- which is slated to fund the takeout -- told Finish Line that it was "extremely concerned" about Genesco's financial health and might withhold financing if Genesco has undergone a "Material Adverse Effect" as defined in the related agreement.

Shares of Nashville, Tenn.-based Genesco were up 1.5% to $47.46; Finish Line, based in Indianapolis, slipped 0.6% at $5.26.