This account is pending registration confirmation. Please click on the link within the confirmation email previously sent you to complete registration.
Need a new registration confirmation email? Click here
Stocks Under $10 with 50-100% upside potential - 14 days FREE!

NeurogesX Climbs on Pain Patch Data

Shares of NeurogesX (NGSX) climbed Tuesday after the biopharmaceutical company announced positive top-line results from a phase III trial of NGX-4010, its dermal pain patch for patients with postherpetic neuralgia, or PHN, a frequent neuropathic pain condition affecting up to one in five shingles patients.

The company said the study met its primary endpoint of reducing pain for eight weeks, with a 32% reduction in pain from the baseline from a 60-minute application, compared with a 24% reduction in pain from the control group. The company said that all secondary endpoints were met as well, including significant results during weeks two through 12, and the initial safety analysis was consistent with the safety profile observed in a previous phase III study on the patch.

The non-narcotic patch contains synthetic Capscaicin, the active component of chili peppers, which is absorbed into the skin without significant absorption into the bloodstream. NeurogesX is also studying NGX-4010 in a second phase III trial on painful HIV-associated neuropathy (HIV-DSP), and top-line results from that study are expected in the first half of 2008.

The company plans to submit a new-drug application with the Food and Drug Administration in the second half of 2008 for treatment of both PHN and HIV-DSP. The patch has been granted orphan-drug status and fast-track designation from the FDA for HIV-DSP. NeurogesX said it's also on track to complete a filing for European regulatory approval in 2007 for a broad indication of peripheral neuropathic pain, including PHN, HIV-DSP and painful diabetic neuropathy (PDN).

Shares rose $1.32, or 18%, to $8.38 in recent trading Tuesday.

To watch CEO Anthony DiTonno discuss the pain patch in a June interview with TheStreet.com TV, click here.

Select the service that is right for you!

COMPARE ALL SERVICES
Action Alerts PLUS
Try it NOW

Jim Cramer and Stephanie Link actively manage a real portfolio and reveal their money management tactics while giving advanced notice before every trade.

Product Features:
  • $2.5+ million portfolio
  • Large-cap and dividend focus
  • Intraday trade alerts from Cramer
  • Weekly roundups
TheStreet Quant Ratings
Try it NOW
Only $49.95/yr

Access the tool that DOMINATES the Russell 2000 and the S&P 500.

Product Features:
  • Buy, hold, or sell recommendations for over 4,300 stocks
  • Unlimited research reports on your favorite stocks
  • A custom stock screener
  • Upgrade/downgrade alerts
Stocks Under $10
Try it NOW

David Peltier, uncovers low dollar stocks with extraordinary upside potential that are flying under Wall Street's radar.

Product Features:
  • Model portfolio
  • Stocks trading below $10
  • Intraday trade alerts
  • Weekly roundups
Dividend Stock Advisor
Try it NOW

Jim Cramer's protege, David Peltier, identifies the best of breed dividend stocks that will pay a reliable AND significant income stream.

Product Features:
  • Diversified model portfolio of dividend stocks
  • Alerts when market news affect the portfolio
  • Bi-weekly updates with exact steps to take - BUY, HOLD, SELL
Real Money Pro
Try it NOW

All of Real Money, plus 15 more of Wall Street's sharpest minds delivering actionable trading ideas, a comprehensive look at the market, and fundamental and technical analysis.

Product Features:
  • Real Money + Doug Kass Plus 15 more Wall Street Pros
  • Intraday commentary & news
  • Ultra-actionable trading ideas
Options Profits
Try it NOW

Our options trading pros provide daily market commentary and over 100 monthly option trading ideas and strategies to help you become a well-seasoned trader.

Product Features:
  • 100+ monthly options trading ideas
  • Actionable options commentary & news
  • Real-time trading community
  • Options TV
To begin commenting right away, you can log in below using your Disqus, Facebook, Twitter, OpenID or Yahoo login credentials. Alternatively, you can post a comment as a "guest" just by entering an email address. Your use of the commenting tool is subject to multiple terms of service/use and privacy policies - see here for more details.
Submit an article to us!
DOW 17,071.84 +128.03 0.76%
S&P 500 1,977.74 +10.17 0.52%
NASDAQ 4,437.5830 +22.0930 0.50%

Brokerage Partners

Rates from Bankrate.com

  • Mortgage
  • Credit Cards
  • Auto
Advertising Partners

Free Newsletters from TheStreet

My Subscriptions:

After the Bell

Before the Bell

Booyah! Newsletter

Midday Bell

TheStreet Top 10 Stories

Winners & Losers

Register for Newsletters
Top Rated Stocks Top Rated Funds Top Rated ETFs