Stockpickr Lists: Dade Behring Hits a High

Editor's Note: In this feature from Stockpickr, we highlight lists of stocks that have made new highs, lows or seen other unusual activity.

Rising on Unusual Volume: Dade Behring Holdings(DADE) vaulted 33% on trading more than 15 times its average three-month volume Wednesday after the clinical diagnostic instrument maker agreed to be acquired by Siemens(SI) for $77 a share in cash. Shares advanced $18.35 to $74.26.

52-Week Highs: Dade Behring also hit a 52-week high.

Biggest % Gainers: BladeLogic(BLOG) skyrocketed 46% after the data-center automation-software company's initial public offering. The company sold 3.94 million of the 5 million shares. Underwriters have an option for another 750,000 shares. Shares advanced $8.07 to $25.07.

52-Week Lows: GPC Biotech(GPCB) plummeted 35% after a Food and Drug Administration advisory panel recommended that the agency wait for more information before approving its prostate-cancer drug satraplatin. The news sunk shares of partner Spectrum Pharmaceuticals(SPPI), which has some commercialization rights, as well as Germany-based GPC, which declined $7.20 to $13.16.

Biggest % Losers: GPC Biotech also hit a 52-week low.

Stocks With Unusual Option Activity: Gas pipeline operator Williams Cos.(WMB) was experiencing unusual option activity. Senior Vice President Ralph A. Hill reported in a Securities and Exchange Commission filing Wednesday that he exercised options for 51,850 shares of common stock under a prearranged trading plan, according to the Associated Press. The shares, costing between $9.93 to $28.98 apiece, were then sold for $35.25 apiece. Shares closed up 15 cents to $33.31.

Forum of the Day

Beach Bunny Enterprises solicits ideas about how to determine stops in a stock position.

Do You Know the Answer?

Siemens is down about $8. What do I do now? Buy more or go cry in the corner? asks jaygeddes.

Feeling Lucky?

And finally, try picking a random portfolio suited to do-it-yourselfers with more detailed analysis at I'm Feeling Lucky.

>To order reprints of this article, click here: Reprints