Stockpickr Lists: Alnylam Spikes After Roche Deal

Editor's Note: In this feature from Stockpickr, we highlight lists of stocks that have made new highs, lows or seen other unusual activity.

Biggest % Gainers: Alnylam(ALNY Quote) rocketed 51% Monday after announcing that it would collaborate with Roche on its RNAi technology. Roche will pay $331 million in upfront costs and equity investments and the deal could eventually be worth $1 billion, the companies said. RNAi technology is a method for turning off genes, therefore potentially preventing disease-causing proteins from being made. Alnylam shares climbed $7.92, reaching $23.12.

52-Week Highs: First Solar(FSLR Quote) soared 23% to a 52-week high after the maker of solar modules entered into a five-year agreement worth nearly $1.3 billion that will produce 685 megawatts of solar power. The company also entered into long-term agreements with EDF Energies Nouvelles and Sechilienne-Sidec. The company closed up $23.05 at $119.34.

Rising on Unusual Volume: First Solar was also experiencing a 360% increase in average trading volume.

Biggest % Losers: Rosetta Resources(ROSE Quote) plunged 12% after the company said Chairman, President and CEO Bill Berilgen has resigned. The oil and gas company closed Monday trading down $2.66 to $19.25.

52-Week Lows: Lexmark(LXK Quote) dropped 6.4% to a 52-week low after warning that second- and third-quarter earnings would miss estimates. The company sees adjusted earnings of 62 cents to 67 cents a share during the second quarter on a revenue decline of about 2%. The printer maker tumbled $3.15 to $46.25.

Stocks With Unusual Option Activity: ConocoPhillips(COP Quote) was experiencing unusual options activity as the stock traded up $3.01, or 3.7%, to $84.05.

Latest Activist Situations: Spencer Capital disclosed a 6.8% stake in Borders Group(BGP Quote). William Ackman's Pershing Square Capital also owns an 11.7% stake in the bookseller. Pershing Square also holds a big stake in Borders' rival Barnes and Noble(BKS Quote). There has been talk in the past he could push the two to merge. Borders closed up 3 cents at $19.31.

Forum of the Day

gmartin1 opens discussion of Video and Computer Game Sector and Stock Analysis.

Do You Know the Answer?

What do think Great Lakes Dredge & Dock Corporation(GLDD Quote) is going to do? asks Steve Fox.

Feeling Lucky?

And finally, try picking a random portfolio suited to do-it-yourselfers with more detailed analysis at I'm Feeling Lucky.