Editor's Note: In this feature from Stockpickr, we highlight lists of stocks that have made new highs, lows or seen other unusual activity.
52-Week Highs: Nuveen Investments(JNC Quote) on Wednesday agreed to be acquired by a private-equity group led by Madison Dearborn Partners, sparking a 17% rise. The $5.4 billion deal sent the Chicago-based investment manager soaring $8.98 to a 52-week high of $63.14. Biggest % Gainers: Fuel Tech(FTEK Quote) jumped 18% after landing a deal with a Hong Kong-based Itochu subsidiary. The two companies will work together on Fuel Tech's Fuel Chem program. The Illinois-based engineering company climbed $5.28 to $33.97. Rising on Unusual Volume: Trading at six times average volume, Chart Industries(GTLS Quote) rose 9% after Ole Slorer upgraded the company to buy from neutral, noting the "industry will improve and expects shares to rise 54% over the next year." Chart Industries makes equipment used to produce and store gases. Shares increased $2.24 to $26.97. Biggest % Losers: After an interim analysis determined Coley Pharmaceutical's(COLY Quote) lung cancer treatment to be ineffective and not worthy of continuation, Pfizer(PFE Quote), which licensed the drug to Coley, discontinued the program. The news sent Coley shares crashing down 59% to $3.46. 52-Week Lows: Coley Pharmaceutical also finished Wednesday trading at a 52-week low. Stocks with Unusual Option Activity: Motorola(MOT Quote) was experiencing unusual options activity Wednesday. Latest Activist Situations: In an amended 13D filing on PHH(PHH Quote), 7.8% shareholder Pennant Capital disclosed a letter to the board of directors reiterating its strong objections to a sale at this time and also outlined several material omissions from the preliminary proxy statement filed June 18. PHH shares barely moved, increasing 2 cents to $31.10.Forum of the Day
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| Dow Jones | S&P 500 | NASDAQ | 10-Year Note | |
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| 10,442.41 | 1,115.55 | 2,237.77 | 36.34 |
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