Shares of Bristol-Myers rose 4.7% to $27.43. Sanofi-Aventis was down 1.7% at $44.57.
On the research front, A.G Edwards upgraded its ratings on Home Depot (HD - Get Report) and Lowe's (LOW - Get Report) to buy from hold. Home Depot was lower by 0.1%, while Lowe's finished with a gain of 0.3%.
Commodities were mainly weaker. Crude oil futures fell $1.41 to close at $54.01 a barrel, and natural gas was off 26 cents to $6.91 per million British thermal units. Gold was lower by $1.50 at $643.20 an ounce, and silver was down 12 cents to finish at $13.25 an ounce.