Jim Cramer's Stop Trading! Toyota Overdrive

It's time to take profits on Express Scripts (ESRX Quote), Jim Cramer said Tuesday on CNBC's Stop Trading! segment.

Shares in the mail-order pharmacy have surged 10% since the company said last week it would offer financial guidance for 2007 today. Cramer predicted at the time that it would pay to buy the stock because management doesn't typically guide till later in November.

On Tuesday, with the stock up 3%, Cramer said it's time to ring the register on Express Scripts after that quick run. "Hogs get slaughtered," Cramer said, adding, "Don't outthink a great trade in health care."

Cramer also said bullish comments from diversified industrial Graco (GGG Quote) show that Home Depot (HD Quote) doesn't know what it's doing and that investors looking to cash in on this stealthy phase of the consumer spending boom should buy rival Lowe's (LOW Quote) instead.

Cramer also said Toyota (TM Quote), eating the Big Three's lunch, is headed for $180 from a recent $123.