Friday's Health Winners & Losers

Shares of Pozen(POZN) were among the worst-performing health-related stocks Friday, plummeting 57% after the Food and Drug Administration requested additional safety information for Trexima, a migraine headache treatment.

The FDA said Trexima, which is being developed by Pozen and GlaxoSmithKline(GSK), is approvable but needs the additional safety information, which may require the companies to conduct new studies. "Pozen and GSK intend to request a meeting with the FDA as quickly as possible to discuss the approvable letter and determine the appropriate next steps to gain full approval," the companies said in a press release. Shares of Pozen were trading down $8.11 to $6, while shares of GlaxoSmithKline dropped 71 cents to $54.69.

Genelabs Technologies(GNLB) rose 8% after the drugmaker said it should have enough cash to fund operations until the beginning of 2008. Including $12.5 million in payments from licensing partner Novartis(NVS), Genelabs expects to have a mid-year cash level of about $15 million. "The recent collaboration provides us with additional needed cash and allows us to continue to move forward with our three separate hepatitis C virus drug discovery programs, two of which now have top-notch corporate partners," the company said.

Separately, Genelabs received notification from Nasdaq officials that it is out of compliance with the market's bid price regulations, which require a stock to not trade below $1 for 30 consecutive business days. Shares of the company had traded below $1 a share until June 2, the last trading day before Genelabs announced a collaboration agreement with Novartis. Since the announcement, shares have traded above the $1 threshold. The company has until Dec. 4 to regain full compliance, it said. In the meantime, the company is in the process of appealing an earlier Nasdaq compliance issue related to minimum shareholder equity and market capitalization requirements. Shares recently were up 15 cents to $2.02.