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FDA Delays Decision on Orexigen Obesity Pill by 3 Months

06/11/14 - 06:48 AM EDT

FDA needs more time to reach agreement on the post-marketing obligation related to the previously agreed upon evaluation of heart-safety related outcomes for Contrave, Orexigen said

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Inovio CEO Preps Retail Investors for Drug Study Failure

06/10/14 - 12:23 PM EDT

Inovio Pharmaceuticals CEO Joseph Kim is walking back expectations for the phase II study of its DNA vaccine VGX-3100 in women with high-grade cervical intraepithelial neoplasia (CIN 2/3), also known as cervical pre-cancerous lesions. Results from the VGX-3100 study should be announced any day, but I suspect Inovio already has data in hand. Why else would Kim be laying the foundation for a massive spin job, if not to cushion the vaccine's failure?

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Achillion Hep C Drug Update is Well Timed

06/10/14 - 08:36 AM EDT

Talk about uncanny timing, one day after Achillion Pharmaceuticals rips higher on takeover speculation, the company announces the lifting of an FDA clinical hold on its lead hepatitis C drug candidate and the start of a new study with a second hepatitis C compound.

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Dendreon CEO Exits Ahead of Big Debt Payment

06/09/14 - 04:38 PM EDT

The desperate Dendreon debacle just descended into despondency with the abrupt departure of Chairman and CEO John Johnson, citing "personal reasons."

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Achillion Pharma Might be Next Hep C Takeout Target

06/09/14 - 09:22 AM EDT

Johnson & Johnson and Abbvie were both reportedly interesting in buying Idenix but lost out to Merck, reports CNBC. Achillion shares are up almost 30% to $TK Monday as investors bet the losers in the Idenix sweepstakes may move on to the next target.

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Merck Buys Idenix for $3.9B in Yet Another Blockbuster Hep C Deal

06/09/14 - 08:27 AM EDT

With Gilead Sciences already marketing the hepatitis C pill Sovaldi and competition from Abbvie-Enanta Pharma and Bristol-Myers Squibb close behind, a lot of investors believed the hepatitis C drug race had transitioned to marketing and away from M&A. But Merck chief scientitist Roger Perlmutter is no dummy, so his decision to spend almost $4 billion on Idenix says the hepatitis C treatment market may have a much longer tail than many believed.

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Celgene to Invest $25M in New Soon-Shiong Healthcare Venture

06/05/14 - 01:42 PM EDT

Celgene CELG is once again partnering with billionaire drug executive Patrick Soon-Shiong. Next Tuesday, Celgene will announce a $25 million investment in NantHealth, a healthcare technology company founded Soon-Shiong, TheStreet has learned.

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Northwest Bio Fuzzier on Cancer Vaccine Study Patient Enrollment

06/05/14 - 08:30 AM EDT

On Wednesday afternoon during a presentation at an investor conference, Northwest Bio CEO Linda Powers once again offered conflicting language on the timeline for enrollment of 312 glioblastoma patients in the phase III study of the experimental cancer vaccine DC-Vax.

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Prosensa to Seek U.S. Approval for DMD Drug

06/03/14 - 07:39 AM EDT

Prepare now for the most epic, two-day FDA advisory panel sometime in the middle of 2015: Prosensa and Sarepta Therapeutics with their respective and competitive exon 51-skipping therapies against Duchenne muscular dystrophy (DMD).

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Incyte's 'IDO' Cancer Immunotherapy Causes Investor Scrum at ASCO '14

06/02/14 - 03:20 PM EDT

We just got our first look at the clinical activity of Incyte's immuno-oncology candidate INCB024360 ('360) dosed at 50 mg and combined with Bristol-Myers Squibb's BMY Yervoy in melanoma patients. The Wall Street scrum around the Incyte poster was insane.

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Adam Feuerstein is a senior columnist at TheStreet in charge of covering biotechnology and pharmaceutical stocks.

Feuerstein has been a financial journalist for more than 20 years. He joined TheStreet in 2001, leaving in 2005 for a two-year stint as a biotech analyst for a New York-based investment management firm. Feuerstein rejoined TheStreet in 2007. Prior to his work at TheStreet, Feuerstein wrote about Internet startups and business software for Upside.com. Covering the dot-com boom and bust of the 1990s and early 2000s made Feuerstein very cynical, a trait he applies to great effect by highlighting the often-overlooked risks of biotech stock investing. In what can only be considered a high compliment, a particularly promotional sell-side analyst once warned his clients that Feuerstein "attacks viciously".

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Feuerstein lives near Boston with his wife, two kids and a yellow lab-golden retriever named Max. When Feuerstein is not writing article and blog posts for TheStreet, he's tweeting. In fact, when Feuerstein is working, he's tweeting. All the time. He also runs, bikes, watches a lot of English soccer matches (Go Spurs!) and loves to cook.

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Markets

DOW 17,071.22 -41.93 -0.24%
S&P 500 1,977.80 -5.05 -0.25%
NASDAQ 4,505.8520 -6.3420 -0.14%

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