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Page 4 of 589

CTI Biopharma Posts Positive Myelofibrosis Study Results

By Adam Feuerstein

CTI Biopharma's experimental drug pacritinib significantly reduced the spleen size in patients with myelofibrosis compared to patients treated with best alternative care.

08:15AM 03/09/15

Biotech Stock Mailbag: Next Biotech Takeout Targets, NewLink Genetics

By Adam Feuerstein

Biotech columnist Adam Feuerstein answers readers' questions about health care companies.

05:30AM 03/06/15

AbbVie Buys Pharmacyclics for $21B to Get Half of Big Cancer Drug

By Adam Feuerstein

AbbVie announced it is buying cancer drug-maker Pharmacyclics for $21 billion.

10:05AM 03/05/15

AbbVie Spending Historic Amount of Cash to Buy Half of a Cancer Drug

By Adam Feuerstein

The $21 billion price tag for Pharmacylics only earns AbbVie rights to 50% of the blood cancer drug Imbruvica.

06:38AM 03/05/15

Bristol-Myers' Cancer Immunotherapy Opdivo Wins Approval to Treat Lung Cancer

By Adam Feuerstein

The new Opdivo approval covers patients with squamous non-small cell lung cancer no longer responsive to chemotherapy, according to an announcement made the FDA.

01:47PM 03/04/15

Regulators Want Drug Companies to Be Honest About FDA

By Adam Feuerstein

The Securities and Exchange Commission's top cop wants drug companies to be more transparent with investors about their dealings with the U.S. Food and Drug Administration.

01:08PM 03/04/15

Orexigen Weight-Loss Pill Shows Surprise Heart-Safety Benefit

By Adam Feuerstein

Obese Americans taking Contrave to lose weight cut their risk of having a heart attack, stroke or dying from heart disease by almost half compared to people taking a placebo.

11:51AM 03/03/15

MannKind Rating, Price Target Are Cut by Goldman on Slow Afrezza Launch

By Adam Feuerstein

The slow commercial launch of the inhaled insulin Afrezza coupled with growing downward pricing pressure for all diabetes products compels Goldman Sachs to slap a 'sell' rating on MannKind.

08:16AM 03/03/15

Athersys Lands Japan Partner for Stroke Therapy Ahead of Key Study Data

By Adam Feuerstein

Chugai decision to license MultiStem for Japan will look prescient or foolish depending on the stem cell therapy's performance in an ongoing phase II study of stroke patients.

09:38AM 03/02/15

MannKind's Afrezza Earns Lackluster Review from Independent Drug Arbiter

By Adam Feuerstein

Afrezza is "modestly effective" at reducing blood glucose and its long-term safety is unknown, according to a review of the inhaled insulin published this week by The Medical Letter.

08:15AM 03/02/15

Page 4 of 589

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