Multinationals Move on Nanotech

03/30/07 - 01:21 PM EDT

ALTI , FEIC , PXN , GE , DD , BF , ROH , ELN , MRK , ABT  
Kevin Kelleher

Updated from March 28

We all knew this was going to happen.

Nanotechnology has become the neglected stepchild of the markets. The hype and fervor surrounding it a few years ago gave way to warnings that the science would yield precious few applications -- and profit -- for years.

Then came disappointment and then, in the minds of investors at least, oblivion.

Aside from some erratic stocks, like Altair Nanotechnologies (ALTI Quote), whose shares are volatile as a result of perennial speculation, and the even-rarer company turning a profit, like electron-microscope maker FEI , companies toiling in science on the nanoscale have been quietly treading water.

A nanotech exchange-traded fund representing an index of stocks that was set up by Lux Research, a New York-based firm focusing on nanotechnology, has traded sideways. The PowerShares Lux Nanotech ETF (PXN Quote) was recently trading off 0.8% to $17.27. A year ago, it was trading at $18.03.

And when the Small Times, a publication devoted to the nanotech industry, appraised the state of 2006 venture investing in the new science, it summed it up this way: "Disappointing ... Just add 'extremely' for public market transactions."

The $650 million in venture money invested in nanotech start-ups last year was far below the $1 billion-plus in 2005, and $172 million of that went to three start-ups: NeoPhotonics, Nanosolar and Nanosphere.

So dim is the view that public and private investors have taken of the one-time hotbed of innovation that news reports have appeared suggesting that the U.S. might fall behind other emerging economies, especially China.

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